All applications to date that have been submitted to the Food and Drug Administration (FDA) by May 14 for non-tobacco nicotine (NTN) products have been processed, and 95% have been assessed to determine if they meet the minimum requirements to be accepted for further review.
As of Oct. 7, 2022, the FDA has issued Refuse to Accept (RTA) letters for more than 889,000 out of the 1 million applications for products containing non-tobacco derived nicotine or synthetic nicotine, according to the National Association of Tobacco Outlets (NATO).
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